Research Projects
Single Dose Drug Study
What: A research study to see if medication can treat abnormal brain electrical activity
Who: Adults 18-45 years old diagnosed with Fragile X Syndrome and an IQ less than 85
Pay: Up to $500 plus travel reimbursement
Contact: Sarah.Richter@cchmc.org
Characterizing the Biology of FXS
Who: Anyone
What: A wide variety of optional tasks, including blood draws, cognitive testing, neuropsychological games, parent measures, EEG, MRI, eye tracking tasks
Why: The purpose of this study is to help us understand the biology of FXS by comparing data from people with FXS to typically developing individuals and individuals with other neurodevelopmental disorders.
Contact: Allison.Lacroix@cchmc.org
Autism Spectrum Disorder and Depression Study
Who: Teens and young adults (13-26 years old) who have ASD and major depressive disorder (MDD) may be eligible.
What: A research study to evaluate the efficacy of repetitive Transcranial Magnetic Stimulation (rTMS) in reducing treatment resistant depressive symptoms in people with autism spectrum disorder (ASD).
Why: To better understand how to treat depression in this population.
Contact: Priya.Ramesh@cchmc.org
Infant and Toddler Brain Function Study
Who: Infants and young toddlers with FXS
What: Multiple language measures & assessments, EEG, fNIRS
Why: This study uses a cap that monitors blood flow and electrical activity in the brain while the participant listens to sounds. The study’s goal is to find a link between brain activity and language impairment.
Contact: Kara.Snyder@cchmc.org
FORWARD MARCH Study
Who: People with FXS born between 2003 and 2017
What: Parent measures, cognitive testing and clinician forms during regularly scheduled clinic visits
Why: The purpose of this research study is to create a way to collect and combine data about people with fragile X syndrome (FXS) from clinics across the United States. This data will help establish the best ways to evaluate and treat people with FXS.
Contact: Ryan.Zix@cchmc.org
ENTRAIN
Who: Children 5 to 10 years old
What: A study to see if listening to different tones can help improve learning and sensory symptoms in children with FXS. ASD and healthy controls are needed for comparison.
Contact: Lynxie.Voorhees@cchmc.org
EEG Study of Brain Activity
Who: People 8-12 years old or 18+ with FXS and IQ < 85 OR typically developing controls
What: Clinical assessments, parent measures, cognitive testing, neuropsychological games, EEG and eye tracking tasks
Why: his study is looking at how the brain works and changes over time in FXS. It is a correlational study that enrolls individuals with FXS, their family members, and control groups.
Contact: Allison.Lacroix@cchmc.org